In search of molecular mechanisms underlying sex differences in cardiac arrythmia

9 May 2022, 16:00:00
Creek Street
Linköping

In general, women are at increased risk of  suffering from cardiac arrhythmias compared to men. This has been  suggested to be due to distinct hormone profiles of steroid sex hormones  like  estrogen, progesterone and testosterone between women and men, which  contributes to differences in cardiovascular electrophysiology between  the sexes. However, there are limited mechanistic insights into how sex  hormones modulate the activity of many of the  proteins critical for tuning cardiac function. In this project, we aim  to understand how the female steroid sex hormone modulates one of the  key cardiac ion channels.

In search of molecular mechanisms underlying sex differences in cardiac arrythmia

Sara Liin

Sara has gotten her PhD in Neurobiology at Linköping University and is now an Associate Professor with her own lab group. She was awarded the Eric K Fernström award for young scientists last year. Sara’s aim is to try to understand how mutated ion channels can cause disease and how to develop new treatment strategies.